Journal: Frontiers in Neuroscience
Article Title: Selective activation of the hypothalamic orexinergic but not melanin-concentrating hormone neurons following pilocarpine-induced seizures in rats
doi: 10.3389/fnins.2022.1056706
Figure Lengend Snippet: Sleep-wake cycle was altered following pilocarpine-induced seizures. (A) Sleep-wake cycle was analyzed based on 24 h EEG and EMG signals collected before and after pilocarpine-induced status epilepticus (SE). Shown here are two 5 min EEG and EMG signals at 10 a.m. from a rat before and after SE, respectively. Blue lines indicate 10 s epochs. The sleep-wake state for each 10 s epoch was designated as in (B) . (C) Bar graph showing that rats displayed increased wake state and decreased REM and NREM state 1 day after SE. * P < 0.05, *** P < 0.001, n = 3, two-way ANOVA.
Article Snippet: EEG and EMG signals were amplified (A-M systems, USA) and filtered (EEG band pass filtered at 0.75–20 Hz and EMG low pass filtered at 20 Hz).
Techniques: